Want to get involved?

Participate in Trials

Do You Have Knee Osteoarthritis?

We’re looking for people with knee osteoarthritis to wear the Cionic Neural Sleeve and participate in a research study.


The Cionic Neural Sleeve is worn on the leg to measure how muscles behave and assist in how the body moves. It is the first system to combine sensing, analysis, and augmentation, delivering Functional Electrical Stimulation (FES) to the four major muscle groups of the leg. The Cionic Neural Sleeve communicates to a cell phone or tablet using Bluetooth technology, and is capable of stimulating muscle contractions (manually or algorithmically) that may enhance walking and muscle conditioning.1

Study Purpose

This is a study to investigate whether stimulation assisted activity provided by the Cionic Neural Sleeve can delay muscle atrophy compared to unstimulated activity in those with knee osteoarthritis.

Ideal Candidates

You may be able to join if you…

  • Are an adult between the ages of 22 and 75
  • Are able to walk 10-30 minutes throughout the day, for 3 days a week
  • Have impaired strength in your leg(s), with one side more impacted than the other
  • Have access to a smartphone (iPhone or Android preferred)
  • Are located in the Bay Area
  • Are willing to make 3 visits to the CIONIC lab in San Francisco
  • You are not able to join if you…

  • Currently receive physical therapy treatment
  • Have limited/no response to electrical stimulation
  • Have a history of falls greater than once a week
  • Have a history of knee surgery
  • What to Expect

    The study will require you to wear the Cionic Neural Sleeve on your most impacted leg while engaging in exercises and walking. You will follow a progressive program of exercises and walking that will be monitored by the Cionic Neural Sleeve. Throughout the study, you will make 3 visits to the CIONIC lab in San Francisco, where we will test your lower limb strength, ask you to walk for 10 meters at a time, walk for 6 minutes at a time, and answer some questionnaires. Each lab visit may take up to 90 minutes in duration.

    Your participation in the study is expected to take 12 weeks, and you will be compensated with a $50.00 Amazon gift card for your time.

    Want more information?

    You can reach the study team by email at trials@cionic.com.

    Safety & COVID Precautions:

    Your safety is our primary concern and we have implemented a safety and sterilization protocol in response to COVID-19. This includes:

  • Pre and Post cleaning to disinfect all surfaces, common areas, and testing space
  • Pre and Post cleaning to disinfect the Cionic Sleeve, chairs, and railings (everything you would touch as a participant)
  • The number of people allowed at the research site will be limited
  • All people entering the site will be asked about any recent COVID exposures
  • The research team will wear masks upon request by the participant to minimize exposure to communicable diseases
  • 1 The Cionic Neural Sleeve is a Food and Drug Administration (FDA)-cleared Class 2 medical device.

    Your privacy is important to us. We don’t share your personal information with anyone.

    1606 Stockton St. - Suite #1
    San Francisco, CA, 94133
    ph: +1 (888) 481-3724